Biosensors

Garant předmětu:

Bohuslav Rezek

Přednášející:

Bohuslav Rezek

Cvičící:

Bohuslav Rezek

Předmět zajišťuje:

katedra fyziky

Anotace:

This course introduces the physical, electronic, biological principles of biosensors and provides information on past, present and future technologies. Various mechanisms and sensor concepts for specific applications (such as detection of glucose, urea, proteins, cells, bacteria, etc.) are explained. In addition, the course introduces the use of modern nanostructures and nanomaterials in biosensors to achieve reliable and sensitive devices for diagnosis at the point of care, in food safety or environmental monitoring. We will also discuss current challenges and future perspectives for various applications of biosensors.

Požadavky:

Students pass the exam by written test and oral examination. Students prepare reports from laboratory exercises.

Osnova přednášek:

1.Overview of biosensors - Introduction and concept of biosensor

2.Biosensor development - ideal biosensor characteristics

3.Bioreceptor - catalytic (equilibrium) and affinity (equilibrium)

4.Surface Function - Physical and Chemical Immobilization

5.Electrochemical and Electrochemiluminescence - Overview and Applications

6.Optical - fluorescence and colorimetric study

7.Field controlled transistors - Sensors and applications

8.Nanobiosectors - top down (nanostructures)

9.Nanobiosectors - bottom up (nanomaterials)

10.BioMEMS / NEMS - Microfluidic, SAW

11.Application of biosensors - market for health care

12.Reliability of biosensors - in food and environment

13.New trends in biosensors - wearable biosensors, laboratory on chip

14.Current global biosensors challenges and future developments, final summary

Osnova cvičení:

The laboratory exercises introduce the construction and functional principles of biosensors in a practical and entertaining way. Exercises take place in the form of independent work of students in the laboratory and demonstrations.The exercises also include an excursion to collaborating research institutes.

Cíle studia:

Studijní materiály:

[1] New Perspectives in Biosensors Technology and Applications, Intech 2011, ISBN 978-953-307-448-1, doi:10.5772/936

[2] Biosensors, InTech 2010, ISBN 978-953-7619-99-2, doi:10.5772/45616

[3] Biosensors: fundamentals and applications, Oxford University Press 1989, ISBN 0198547455

Poznámka:

Rozvrh na zimní semestr 2024/2025:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
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Út	místnost T2:B2-48 Rezek B. 15:15–17:00 (přednášková par. 1) Dejvice Konzultačnímístnost T2:B2-39e Rezek B. 17:00–18:45 (přednášková par. 1) Dejvice Cvičebna
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Rozvrh na letní semestr 2024/2025:

Rozvrh není připraven

Předmět je součástí následujících studijních plánů:

• Medical Electronics and Bioinformatics - Specialization Image Processing (povinně volitelný předmět)
• Medical Electronics and Bioinformatics - Specialization Signal Processing (povinně volitelný předmět)
• Medical Electronics and Bioinformatics - Specialization Bioinformatics (povinně volitelný předmět)
• Medical Electronics and Bioinformatics - Specialization Medical Instrumentation (povinně volitelný předmět)