Materials for Biomedicine

Garant předmětu:

Ladislav Cvrček, Petr Špatenka

Lecturer:

Ladislav Cvrček, Petr Špatenka

Tutor:

Ladislav Cvrček, Petr Špatenka

Supervisor:

Department of Materials Engineering

Synopsis:

Introduction to the properties of the biological environment, the response of materials to the effects of the living system, function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion). Tribological properties of materials - friction, abrasion. Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites. Effect of chemical properties of biomaterial surface and corrosion resistance on biocompatibility, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism. Clinical use of biomaterials. Biocompatibility tests (in vitro, in vivo). Standardization and administration of biomaterials. Selection and design of biomaterial for application.

•Biocompatibility - Concepts and Definitions; properties of the biological environment

•Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites

•Function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion).

•Methods of determining the structure and composition of the material

•Surface properties of biomaterials (topographic, tribological, chemical)

•Functional properties of biomaterials, degradation

•Surface treatment - thin layers and coatings

•Immune system, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism

•Biocompatibility tests, sterilization

•Cell interactions with the surface - effect of biomaterial surface properties on biocompatibility

•Development of biocompatible material - endoprosthesis stem (PEEK + C fiber composite), cardiac pump (TiN

layer), plasma spray TiNi

Requirements:

Syllabus of lectures:

Biocompatibility - Concepts and Definitions; properties of the biological environment

•Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites

•Function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion).

•Methods of determining the structure and composition of the material

•Surface properties of biomaterials (topographic, tribological, chemical)

•Functional properties of biomaterials, degradation

•Surface treatment - thin layers and coatings

•Immune system, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism

•Biocompatibility tests, sterilization

•Cell interactions with the surface - effect of biomaterial surface properties on biocompatibility

•Development of biocompatible material - endoprosthesis stem (PEEK + C fiber composite), cardiac pump (TiN

layer), plasma spray TiNi

Syllabus of tutorials:

Study Objective:

Study materials:

•Biomaterials science: an introduction to materials in medicine. 3rd ed. Editor B. D. RATNER. Amsterdam: Elsevier, 2013. ISBN 978-0-12-374626-9.

•BHUSHAN, Bharat. Principles and applications of tribology. Second edition. Hoboken: Wiley, John Wiley & Sons, 2013. ISBN 9781119944546.

•GRIESSER, Hans J. Thin film coatings for biomaterials and biomedical applications. Amsterdam: Elsevier, Woodhead Publishing, [2016].

Note:

Time-table for winter semester 2023/2024:

Time-table is not available yet

Time-table for summer semester 2023/2024:

Time-table is not available yet

The course is a part of the following study plans: