Materials for Biomedicine

Course guarantor:

Lecturer:

Tutor:

Supervisor:

Department of Materials Engineering

Synopsis:

Introduction to the properties of the biological environment, the response of materials to the effects of the living system, function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion). Tribological properties of materials - friction, abrasion. Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites. Effect of chemical properties of biomaterial surface and corrosion resistance on biocompatibility, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism. Clinical use of biomaterials. Biocompatibility tests (in vitro, in vivo). Standardization and administration of biomaterials. Selection and design of biomaterial for application.

Biocompatibility - Concepts and Definitions; properties of the biological environment

Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites

Function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion).

Methods of determining the structure and composition of the material

Surface properties of biomaterials (topographic, tribological, chemical)

Functional properties of biomaterials, degradation

Surface treatment - thin layers and coatings

Immune system, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism

Biocompatibility tests, sterilization

Cell interactions with the surface - effect of biomaterial surface properties on biocompatibility

Development of biocompatible material - endoprosthesis stem (PEEK + C fiber composite), cardiac pump (TiN

layer), plasma spray TiNi

Requirements:

Syllabus of lectures:

Biocompatibility - Concepts and Definitions; properties of the biological environment

Mechanical properties of biomaterials: metals, ceramics, plastics, carbon, composites

Function and degradation of materials in vitro and in vivo (plastics, metals, dissolution, corrosion).

Methods of determining the structure and composition of the material

Surface properties of biomaterials (topographic, tribological, chemical)

Functional properties of biomaterials, degradation

Surface treatment - thin layers and coatings

Immune system, haemocompatibility, allergic reactions, carcinogenicity; adaptation of the organism

Biocompatibility tests, sterilization

Cell interactions with the surface - effect of biomaterial surface properties on biocompatibility

Development of biocompatible material - endoprosthesis stem (PEEK + C fiber composite), cardiac pump (TiN

layer), plasma spray TiNi

Syllabus of tutorials:

Study Objective:

Study materials:

Biomaterials science: an introduction to materials in medicine. 3rd ed. Editor B. D. RATNER. Amsterdam: Elsevier, 2013. ISBN 978-0-12-374626-9.

BHUSHAN, Bharat. Principles and applications of tribology. Second edition. Hoboken: Wiley, John Wiley & Sons, 2013. ISBN 9781119944546.

GRIESSER, Hans J. Thin film coatings for biomaterials and biomedical applications. Amsterdam: Elsevier, Woodhead Publishing, [2016].

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: