General Pharmacology

Garant předmětu:

Stanislav Smrček

Lecturer:

Stanislav Smrček

Tutor:

Supervisor:

Department of Nuclear Chemistry

Synopsis:

The lecture deals with use of organic compounds in human pharmacotherapy. The relation between chemical constitution and biological activity is discussed. In the first part the basic subjects of general pharmacology (distribution in organisms, kinetic parameters, biotransformation, dose response etc.) are explained. The second one deals with pharmacological groups of therapeutically useful substances. The definition and explanation of common pharmacotherapeutical terms and a survey of pharmaceutics informatics and drug forms are also involved.

Requirements:

Knowledge of chemistry on the level of bachelor of chemistry and completed course of fundamentals of nuclear chemistry.

Syllabus of lectures:

1. Pharmaceuticals names, databases systems, drugs forms.

2. Anatomic-therapeutic-chemical clasification (ATCC system), pharmacopoiea.

3. Alimentary tract therapeuticals.

4. Drugs of cardiovascular system, influence of blood parameters.

5. Dermatologics.

6. Pharmaceuticals for urogenital system, sexual hormones.

7. Antiinfective drugs.

8. Cytostatics and immunomodulators.

9. Drugs of musculoskeletal system.

10. Drugs of nervous system.

11. Drugs for respiratory tract.

12. Drugs of sense organs.

Syllabus of tutorials:

Study Objective:

The course provides the students with the knowledge of the therapeutic and diagnostic applications of chemical substances - pharmaceuticals.

The students will acquire competence to assess the action of pharmaceutically active compounds at their application in connection with mechanisms of action.

Study materials:

Key literature:

1.Luellmann H., Mohr K., Hein L., Bieger D.: Color atlas of Pharmacology, 3rd edition, Thieme Stuttgart, New York 2005.

Recommended literature:

1.Katzung B.G.: Basic&Clinical Pharmacology, McGrav-Hill Medical 2009.

Note:

Time-table for winter semester 2023/2024:

Time-table is not available yet

Time-table for summer semester 2023/2024:

Time-table is not available yet

The course is a part of the following study plans:

• Jaderná chemie (elective course)