Cell biomechanics

Garant předmětu:

Matej Daniel

Lecturer:

Matej Daniel

Tutor:

Matej Daniel

Synopsis:

The aim of the course is to explain basic structural and functional cell units and their importance for keeping mechanical integrity and ensuring motion. The subject is based on application of mechanical structure analysis to cellular structures.

Structure and morphology

Molecular forces, principles of self-organization

Mechanics of fluid mosaic

Helfrich energy

Mechanical cells with internal overpressure

Entropia of the ideal chain

Entropic elasticity

Elasticity of macromolecules

Elasticity of molecular networks

Tenzegrity principles

Experimental mechanics of molecules

Experimental cell mechanics

Molecular engines

Requirements:

Syllabus of lectures:

Syllabus of tutorials:

Study Objective:

Study materials:

D. Boal (2012). Mechanics of the Cell, Cambridge University Press. ISBN: 9780521130691.

R.B. Phillips, J. Kondev, J. Theriot (2009). Physical Biology of the Cell, Garland Science. ISBN: 9780815344506.

K.A. Dill, S. Bromberg (2015) Molecular Driving Forces: Statistical Thermodynamics in Biology, Chemistry, Physics, and Nanoscience, 2nd Edition 2nd Edition, Garland Science; ISBN: 0815344309.

M. Gardel, Patrick Oakes (2015) Measuring Cell Mechanics. Biota Publishing. ISBN: 1615046992

Note:

Time-table for winter semester 2024/2025:

Time-table is not available yet

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans: