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CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2023/2024
UPOZORNĚNÍ: Jsou dostupné studijní plány pro následující akademický rok.

Genetics and Molecular Biology for Optometrists

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Code Completion Credits Range Language
F7PBOGMB Z,ZK 3 2P+2C Czech
Garant předmětu:
Veronika Vymětalová
Lecturer:
Veronika Vymětalová
Tutor:
Aneta Buchtelová, Veronika Vymětalová
Supervisor:
Department of Natural Sciences
Synopsis:

General genetics: basic genetic expressions. Genotypes and Phenotypes. Mendel´s theory of inheritance. Basis of clinical genetics: heredity of genetic diseases, monogenic autosomal and gonosomal heredity and monogenic autosomal and gonosomal hereditary dominant and recessive disorders, polygenic heredity, examples of hereditary diseases. Mutagenesis: types of mutations and mutations consequences, physical, chemical and biological mutagens. Carcinogenesis, cell cycle regulation, protooncogens, tumor suppressor genes, chromosomal changes in tumors. Clinical cytogenetics. Inborn chromosomal abnormalities numerical and structural, causes of chromosomal abnormalities origin, examples of the most frequent chromosomal abnormalities. Immunogenetics, heredity of blood groups. Prenatal cytogenetic diagnosis - methods, indications, ethic problems in genetics. Molecular cytogenetics, hybridization in situ. Methods in Assisted Reproduction Technology. Molecular biology. Genetic Engineering. DNA cloning. Gene therapy.

Requirements:

credit condition - 80% presence, working at laboratory, successful written test.

Examination: class ticket, succesful mastery of written work

Syllabus of lectures:

1. General genetics: basic genetic expressions. Genotypes and Phenotypes.

2. Mendel´s theory of inheritance.

3. Basis of clinical genetics

4. Monogenic autosomal and gonosomal heredity, examples of hereditary diseases.

5. Polygenic heredity

6. Cell cycle regulation, protooncogens, tumor suppressor genes.

7. Mutagenesis and carcinogenesis

8. Clinical cytogenetics.

9. Prenatal cytogenetic diagnosis - methods, indications, ethic problems in genetics.

10. Molecular cytogenetics, hybridization in situ. Methods in Assisted Reproduction Technology.

11. Molecular biology.

12. Genetic Engineering. DNA cloning.

13. Gene therapy.

Syllabus of tutorials:

1. General genetics.

2. Mendel´s and Morgan theory of inheritance.

3. Cell cycle, Mitosis and Meiosis.

4. Cell cycle, Mitosis and Meiosis.

5. Bacterial genetics.

6. Plant genetics and breeding. Plant genetics models. Animal genetics.

7. Clinical cytogenetics.

8. Clinical cytogenetics.

9. Monogenic autosomal and gonosomal heredity, examples of hereditary diseases

10. Monogenic autosomal and gonosomal heredity, examples of hereditary diseases

11. Polygenic heredity.Imunogenetics.

12. Mutagenesis, protooncogens, tumor suppressor genes.

13. Molecular biology.

Study Objective:
Study materials:

[1] NUSSBAUM R.L. et al. Thompson and Thompson genetics in medicine, W.B. Saunders, Philadelphia 2001, USA, ISBN: 0-7216-6902-6.

[2] NORTHROP, R.B., CONNOR, A.N.. Introduction to molecular biology, genomics, and proteomics for biomedical engineers. Boca Raton: CRC Press/Taylor & Francis, 2009. ISBN: 9780429148767.

[3] ALBERTS, B. et al. Molecular biology of the cell: reference edition. 5th ed. New York: Garland Science, 2008. ISBN: 978-0-8153-3218-3.

Note:
Time-table for winter semester 2023/2024:
Time-table is not available yet
Time-table for summer semester 2023/2024:
06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
roomKL:B-220
Vymětalová V.
10:00–11:50
(lecture parallel1)
Kladno FBMI
Učebna
Tue
roomKL:B-223
Buchtelová A.
10:00–11:50
(lecture parallel1)
Kladno FBMI
Lab. mikroskopických praktik
roomKL:B-223
Buchtelová A.
12:00–13:50
(lecture parallel1)
Kladno FBMI
Lab. mikroskopických praktik
Wed
Thu
Fri
The course is a part of the following study plans:
Data valid to 2024-04-13
Aktualizace výše uvedených informací naleznete na adrese https://bilakniha.cvut.cz/en/predmet6472406.html