Macromolecular Chemistry for Optometrists

Code	Completion	Credits	Range	Language
F7PBOMCH	Z,ZK	3	1P+1C	Czech

In order to register for the course F7PBOMCH, the student must have successfully completed the course F7PBOCHO in a previous semester.

In order to register for the course F7PBOKC1, the student must have successfully completed or received credit for and not exhausted all examination dates for the course F7PBOMCH.

Garant předmětu:

Jiří Michálek

Lecturer:

Jiří Michálek

Tutor:

Jiří Michálek

Supervisor:

Department of Natural Sciences

Synopsis:

An introduction to macromolecular chemistry with respect to contact lens and spectacle optics materials.

In particular, common types of polymers and their structural units will be discussed, with a focus on selected materials that somehow enter into the manufacturing process of contact lenses, respectively spectacle frames and lenses, including the synthesis of their monomers (MMA, HEMA, MA, NVP, CAB, etc.).

Attention will be paid to the basic concepts and laws in macromolecular chemistry (chain structure, polymerization contraction, glass transition temperature, polymerization degree, molar mass of polymers, types of polymer structures, types of polymerizations and their methods, more emphasis will be placed on radical polymerization with its individual phases). In the context of contact lens materials, copolymerization issues will be explained, including graft and block copolymers. Special attention will be paid to polymer gels, network structure, characterization of gels, rubbery elasticity, hydrogels, polysiloxanes, silicone hydrogels, including their characterization by selected properties (botnation properties, mechanical properties, optical properties) and how to determine them. In addition to the application of hydrogels in medical and technical practice, polymers for spectacle optics and „auxiliary“ polymers used in contact lens manufacturing or packaging (PE, PP, ) will be continuously emphasized. Crosslinking agents, stepwise polyreactions and polymer analogue reactions will also be mentioned.

Requirements:

Credit requirements:

1. Credit with good test results and 70% attendance automatically in the last class, otherwise you must pass the credit test. Illness documented by sick leave or a doctor's report is considered an absence.

2. Basic knowledge continuously verified by tests. The minimum to pass each test is 50% correct answers. Continuous tests are written only once, i.e. without the possibility of correction. The credit test contains 40 questions; to be awarded credit, a student must have 75% correct answers.

Exam requirements:

1. The examination is oral, the examinee is given 3 questions. The exam consists of 2 questions, 2 tests, 2 questions of the exam, 2 questions of the exam, 2 questions of the exam, 2 questions of the exam.

Syllabus of lectures:

- History of macromolecular chemistry, natural and synthetic polymers

- Polymers around us, technical and medical applications of polymers

- Basic concepts: macromolecule, monomer, oligomer, polymer, macromonomer

- Polymerization contraction, chain structure, Tg, rubbery elasticity of polymers

- Polymerisation degree, molar mass of polymers

- Structure of polymers - constitution of macromolecules (linear, branched, cross-linked polymer)

- Structure of polymers - configuration of macromolecules, conformation

- Chain polyreactions: radical polymerization, initiation, types of initiators

- Chain polyreactions: radical polymerization, propagation, termination, transfer reactions

- Chain polyreactions: radical copolymerization, copolymerization parameters, Q,e scheme

- Chain polyreactions: radical copolymerization, alternative and ideal copolymerization, block and graft copolymers

- Chain polyreactions: Methods of performing radical polymerizations: block, solution, suspension and emulsion polymerization

- Stepped polyreactions - comparison of stepped and chain polyreactions

- Staged polyreactions - polycondensation and polyaddition

- Stepwise polyreactions - characteristic bonds formed in a polyreaction

- Staged polyreactions - polyesters, polyamides, polysiloxanes

- Polymer analogue reactions, polyvinyl acetate reactions, cellulose reactions

- Polymer gels, network formation and structure, sol/gel, characterization of gels

- Hydrogels, PHEMA, other glycol methacrylates, PVP

- Hydrogels, GMMA, AAm, MA

- Properties of hydrogels: botnation, optical, surface (contact angle) and methods of their determination

- Hydrogel properties: mechanical and methods of determination

- Synthesis of monomers

- Crosslinking agents

- Silicone hydrogels

- Materials for spectacle optics and an overview of their properties

- Polymer degradation and polymer waste management, toxicity of polymers and monomers

Syllabus of tutorials: