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Organic chemistry 1

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Code Completion Credits Range
15ORCA1 Z 2 2P+2C

In order to register for the course 15ORCA2, the student must have successfully completed or received credit for and not exhausted all examination dates for the course 15ORCA1.

Garant předmětu:
Ján Kozempel
Ján Kozempel, Martin Palušák, Michal Sakmár, Stanislav Smrček, Martin Vlk
Department of Nuclear Chemistry

Structure of organic compounds, properties of covalent bond, reactions on covalent bonds. Nomenclature of organic compounds (main chain, group, locants, prefixes and suffixes) . Spatial structures of organic compounds, double bond isomers, chirality, enantiomers and diastereomeric compounds. Configuration and conformation, relationships. Lewis structures, formal charges, acidity, hard and soft acids and bases. Resonance, aromaticity, classification of substituents, reactivity of polycyclic arenes. Intermediates: carbocations, carbanions, carbenes, radicals - electronic structure. Basic overview on alkanes and cycloalkanes, alkenes, arenes, halogenderivatives, organometallic compounds, alcohols and ethers, organic compounds of sulfur, nitrogen, phosphorus, silicon, other elements and carbonyl compounds chemistry.

Syllabus of lectures:

1.Introduction to organic chemistry, structural theories, main groups of organic compounds, nomenclature basics.

2.Chemical bonds in organic compounds, electronic effects, resonances, isomerism, conformations, configuration, chirality.

3.Alkanes and cycloaclanes – nomenclature, structure, preparation, reactivity.

4.Alkenes, cycloalkenes, polyenes, alkynes – nomenclature, structure, preparation, reactivity.

5.Arenes, theory of aromaticity, nomenclature, structure, preparation, reactivity.

6.Halogen derivatives – nomenclature, structure, preparation, reactivity. Organometallic compounds.

7.Alcohols and Ethers, structure, preparation, reactivity.

8.Sulphides, other compounds of Sulphur, compounds of Phosphorus, Silicon and other elements – nomenclature, structure, preparation, reactivity, their use.

9.Nitro- compounds and amines – nomenclature, structure, preparation, reactivity and their use.

10.Amines – reactivity, reactions of amines as bases and nucleophiles, diazo compounds and their reactions.

11.Carbonyl compounds, structure of carbonyl, reactivity centres, basic reactions of carbonyls.

12.Aldehydes and ketones – nomenclature, structure, preparation, reactivity, addition of carbanions, condensation reactions.

Syllabus of tutorials:

1.Nomenclature of organic compounds.

2.Structure of organic compounds, structural representations, structural models, isomerism.

3.Basics of reactions mechanisms.

4.Basics of organic synthesis.

5.Reactions of alkenes, alkynes.

6.Reactions and preparation of halogen derivatives.

7.Reactions and preparation of alcohols and sulphides.

8.Reactions and preparation of organometallic compounds.

9.Reactions and preparation of amino-, nitro- a diazo- compounds.

10.Condensation reactions and preparation of carbonyl compounds.

Study Objective:

The course of Organic chemistry 1 provides the knowledge of the basic concepts of the structure and nomenclature of organic compounds, reaction mechanisms. Students would gain basic overview on alkanes and cycloalkanes, alkenes, arenes, halogenderivatives, organometallic compounds, alcohols and ethers, organic compounds of sulfur, nitrogen, phosphorus, silicon, other elements and carbonyl compounds chemistry, nomenclature, structure, preparation and use.

The students will acquire competence to apprehend the advanced specialised organic chemistry courses.

Study materials:

Key Literature:

1.J. McMurry: Organic Chemistry, 9th Ed., Brooks/Cole Cengage Learning, 2015

2.F. A. Carey: Organic Chemistry, Mcgraw-Hill Education – Europe, 2016

Recommended Literature:

3.D. E. Lewis: Organic Chemistry – a Modern Perspective, Times Mirror Education Group, Inc. Dubunque 1996

Time-table for winter semester 2023/2024:
Time-table is not available yet
Time-table for summer semester 2023/2024:
Time-table is not available yet
The course is a part of the following study plans:
Data valid to 2024-04-21
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