Macromolecular Crystallography Laboratory 1

Course guarantor:

Tomáš Kovaľ

Lecturer:

Tomáš Kovaľ

Tutor:

Tomáš Kovaľ

Supervisor:

Department of Solid State Engineering

Synopsis:

The subject introduces the students to practical aspects of macromolecular crystallography.

Requirements:

11DMSB - Diffraction methods of Structural Biology

Syllabus of lectures:

Practicals only.

Syllabus of tutorials:

1. Characterization of a macromolecular sample in solution.

2. Crystallization methods.

3. Hands-on experience with in-house X-ray diffractometer.

4. Diffraction data processing.

Study Objective:

The goal of the study is to gain the practical experience in crystallography: sample manipulation, crystallization, in-house data collection, diffraction data processing and evaluation.

Study materials:

J. Marek, Z. Trávníček: Monokrystalová rentgenová strukturní analýza. Univerzita Palackého v Olomouci, Olomouc, 2002.

V. Valvoda, M. Polcarová, P. Lukáč. Základy strukturní analýzy. Karolinum, Praha, 1992.

I. Kraus: Struktura a vlastnosti krystalů. Academia, Praha, 1993.

Note:

Further information:

https://kiplwww.fjfi.cvut.cz/drupal7/?q=11PMK1

Time-table for winter semester 2024/2025:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
Tue
Wed
Thu	room Kovaľ T. 10:00–13:50 (parallel nr.101)
Fri

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans:

• Inženýrství pevných látek (elective course)
• Solid State Engineering (elective course)