Chemistry of the Pharmaceuticals

Course guarantor:

Lecturer:

Tutor:

Supervisor:

Department of Nuclear Chemistry

Synopsis:

The lecture deals with the use of organic compounds in human pharmacotherapy. The relation between chemical constitution and biological activity is in the centre of aspects discussed. In the first part the basic subjects of general pharmacology (distribution in organisms, kinetic parameters, biotransformation, dose response etc.) are explained. The second one deals with pharmacological groups of therapeutically useful substances. The definition and explanation of common pharmacotherapeutical terms, application formulations and examples of pharmaceutical databases are also involved.

Requirements:

Syllabus of lectures:

1.Pharmaceutical nomenclature, databases, application forms, ATCC classification, pharmacopoea.

2.Application, distribution, biotransformation and elimination of drugs.

3.Pharmacon-receptor interactions, evaluation of effects, dose response, side-effects.

4.Pharmacokinetics (single, repeated application, cumulation, elimination changes).

5.General anaesthetics, hypnotics, antiepileptics.

6.Psychopharmacological drugs.

7.Local anaesthetics, analgetics.

8.Cardiovascular drugs.

9.Drugs of vegetative (autonomic) nervous system..

10.Antibiotics, antimycotics, antiparasitic drugs.

11.Drugs of respiratory system, antiasthmatics.

12.Drugs of gastrointestinal system, diuretics.

13.The principles of common diseases pharmacotherapy.

Syllabus of tutorials:

Study Objective:

Study materials:

1.Pharmindex Brevíř; MediMedia Information s.r.o., Praha(aktuální vydání)

2.Hynie, S: Farmakologie v kostce, Triton Praha (2001).

3.Hynie, S.: Základy farmakologie, Triton Praha (1999).

4.Luellman, H., Mohr, K., Ziegler, A., Bieger, D.: Barevný atlas farmakologie, Grada Publishing s.r.o. (2001).

5.Lincová, D., Farghali, H.: Základní a aplikovaná farmakologie, Galén, Karolinum (2002).

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: