Radiopharmaceuticals 2

Course guarantor:

Ján Kozempel

Lecturer:

Ján Kozempel, Marek Moša, Martin Vlk

Tutor:

Supervisor:

Department of Nuclear Chemistry

Synopsis:

The basic principles of nuclear chemistry. A survey of radionuclides used in nuclear medicine. The common methods of radiopharmaceuticals preparations. Quality and control of radiopharmaceuticals.The basic radiopharmaceuticals and their use in human diagnostic and therapy.

Requirements:

Knowledge of chemistry on the level of bachelor of chemistry and completed course of fundamentals of nuclear chemistry.

Syllabus of lectures:

1. Definition and clasification

2. Radionuclides, their selection and preparation

3. Chemical forms

4. Scintigraphic investigation in nuclear medicine

5. Instrumentation and pharmakology in nuclear medicine

6. Nuclear cardiology

7. Nuclear neurology

8. Nuclear nefrology

9. Nuclear oncology

10. Nuclear orthopedy, bone marrow and hematology in scint. picture

11. Other investigation methods in nuclear medicine

Syllabus of tutorials:

Study Objective:

The course provides the students with the knowledge of radionuclides used in nuclear medicine, common methods of radiopharmaceuticals preparations and quality and control of radiopharmaceuticals.

The students will acquire competence to work in the field of radiopharmacy.

Study materials:

Key Literature:

1.European pharmacopoeia, as amended

2.R. P. Baum, F. Rosch (eds): Theranostics, Galium-68, and other Radionuclides, Springer, Heidelberg, 2013, doi: 10.1007/978-3-642-27994-2, ISBN: 978-3-642-27993-5

3.E. Bombardieri, E. Seregni, L. Evangelista, C. Chiesa, A. Chiti (eds.): Clinical Applications of Nuclear Medicine Targeted Therapy, Springer Heidelberg, ISBN: 978-3-319-63066-3, 2018, doi: 10.1007/978-3-31963067-0

Recommended Literature:

1.R. Weissleder, B. D. Ross, A. Rehemtulla, S. S. Gambhir: Molecular Imaging Principles and Practice, McGraw-Hill, New York, 2010 ISBN: 9781607950059

Note:

Time-table for winter semester 2024/2025:

Time-table is not available yet

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans:

• Jaderná chemie (compulsory elective course)
• Radiolgická fyzika (elective course)