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CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2022/2023

Labelled Compounds

The course is not on the list Without time-table
Code Completion Credits Range
15SLOU ZK 2 2+0
Lecturer:
Tutor:
Supervisor:
Department of Nuclear Chemistry
Synopsis:

Basic methods of stable isotope separations, basic methods of the production of important radionuclides, synthesis of organic compound labelled by isotopes of hydrogen, carbon, nitrogen, sulfur, phosphorus, halogens. Application of stable and radioactive nuclides as tracers for elucidation of mechanisms in inorganic chemistry, organic chemistry and biochemistry. Basic theory and application of kinetic and equilibrium isotope effects. Some radioanalytical procedures in biology and medicine.

Requirements:

Knowledge of chemistry on the level of bachelor of chemistry and completed course of fundamentals of nuclear chemistry.

Syllabus of lectures:

1.Basic methods of the stable isotope separation.

2.Production of radionuclides.

3.Synthesis of the compound labelled with hydrogen isotopes..

4.Synthesis of the compound labelled with carbon isotopes

5.Synthesis of the compound labelled with isotopes N, O, S, P.

6.Synthesis of the compound labelled with halogen isotopes

7.Synthesis of the complex compounds labelled with isotopes of metals.

Syllabus of tutorials:
Study Objective:

The course provides the students with the knowledge of basic methods of the production of important radionuclides and methods of synthesis of organic compounds labelled by radionuclides.

The students will acquire competence to work in the field of synthesis of organic compounds labelled by radionuclides.

Study materials:

Key references:

1.Jones J.R. (Editor): Isotopes: Essential Chemistry and Application I. Royal Soc. Chem. 1980.

2.Jones J.R. (Editor): Isotopes: Essential Chemistry and Application II. Royal Soc. Chem. 1988.

Note:
Further information:
No time-table has been prepared for this course
The course is a part of the following study plans:
Data valid to 2022-12-05
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