Hyperthermia

Garant předmětu:

Gerard Van Rhoon

Přednášející:

Gerard Van Rhoon

Cvičící:

Gerard Van Rhoon, David Vrba

Předmět zajišťuje:

katedra biomedicínské techniky

Anotace:

Randomized clinical trials (RCT’s) have been shown significant improvement in clinical outcome when hyperthermia was added to radiotherapy and/or chemotherapy. According to the standards set by the Society of Thermal Medicine (STM); European Society for Hyperthermic Oncology (ESHO) and the Asian Society of Hyperthermic Oncology (ASHO); the benefits of hyperthermia are fully realized when the tumor temperature reaches 39-43 degrees Celsius. The course aims to introduce the benefits of Hyperthermia in Cancer Treatment as well as to introduce the hardware and software equipment.

Požadavky:

In the case of foreign lecturers, there will be a weeklong block of intensive contact education for the number of students at least five. If the number of students is less than five, the course will be self-study with consultations using VoIP (e.g. Skype) and a contact 1-or 2-day seminar. The contact seminar will take place at the FBMI or at the home institution of a foreign lecturer. The subjects are concluded by an oral examination. The student must elaborate a paper on a given topic together with the exam in case of the controlled self-study.

Two laboratory exercises are required for admission to the exam (attested by a protocol signed by the student, the tutor and the supervisor of the course).

The protocols will be archived in the Department for Doctoral Studies.

Osnova přednášek:

Lectures:

1. Thermal biology - hyperthermia and ablation

2. Tumour biology and Physiology

3. Biological basis of thermal dose

4. Bio-heat equation

5. Thermal properties of tissues, Vascular cooling

6. Temperature measurement

7. RF & Microwaves

8. High Intensity Focused ultrasound

9. Heat + radiotherapy, Heat + drugs Novel treatment approaches

10. Clinical Cases: Deep hyperthermia, Superficial hyperthermia, Ultrasound in the brain.

Osnova cvičení:

Laboratory:

1. Creating 3D models by segmenting CT images

2. Treatment Planning for Microwave Hyperthermia

Cíle studia:

Randomized clinical trials (RCT’s) have been shown significant improvement in clinical outcome when hyperthermia was added to radiotherapy and/or chemotherapy. According to the standards set by the Society of Thermal Medicine (STM); European Society for Hyperthermic Oncology (ESHO) and the Asian Society of Hyperthermic Oncology (ASHO); the benefits of hyperthermia are fully realized when the tumor temperature reaches 39-43 degrees Celsius. The course aims to introduce the benefits of Hyperthermia in Cancer Treatment as well as to introduce the hardware and software equipment.

Studijní materiály:

Required:

[1] Wust P."THERMOTHERAPY IN ONCOLOGY UNI-MED, Science, 1st edition 2016,

Recommended:

[1] N. Cihoric, A. Tsikkinis, G. van Rhoon, H. Crezee, D. M. Aebersold, S. Bodis, M. Beck, J. Nadobny, V. Budach, P. Wust, and P. Ghadjar, "Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry,” Int J Hyperthermia, vol. 31, no. 6, pp. 609-14, Sep, 2015.

[2] M. M. Paulides, P. R. Stauffer, E. Neufeld, P. F. Maccarini, A. Kyriakou, R. A. Canters, C. J. Diederich, J. F. Bakker, and G. C. Van Rhoon, "Simulation techniques in hyperthermia treatment planning,” Int J Hyperthermia, vol. 29, no. 4, pp. 346-57, Jun, 2013.

[3] J. E. Johnson, D. G. Neuman, P. F. Maccarini, T. Juang, P. R. Stauffer, and P. Turner, "Evaluation of a dual-arm Archimedean spiral array for microwave hyperthermia,” International Journal of Hyperthermia, vol. 22, no. 6, pp. 475-490, Sep. 2006.

Poznámka:

Modul D

Rozvrh na zimní semestr 2024/2025:

Rozvrh není připraven

Rozvrh na letní semestr 2024/2025:

Rozvrh není připraven

Předmět je součástí následujících studijních plánů: