Biomechanics of aging and pathobiomechanics

Garant předmětu:

Lecturer:

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Synopsis:

The aim of the Biomechanics of aging and pathobiomechanics course is to present current knowledge of the theory of human aging and etiology and pathogenesis of diseases correlated with advanced age. Age-related changes in the mechanical properties of the living organs and tissues are emphasized and an effect of changed mechanical properties on the function of organs is explained in detail.

Cell biology

Organ, organ system, and fundamental pathophysiological concepts

Inflammation

Aging

Biomechanical changes in cardiovascular system associated with aging (heart)

Biomechanical changes in cardiovascular system associated with aging (blood vessels)

Consequences of aging for cardiovascular diseases

Aging and biomechanics of skin

Aging and musculoskeletal system

Diseases of musculoskeletal system

Constitutive modeling with reference to aging (cardiovascular system)

Constitutive modeling with reference to aging (musculoskeletal system)

Mathematical description of tissue remodeling and adaptation

Requirements:

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Study materials:

McDonald R.B. (2014) Biology of aging. Garland Science, New York.

Humphrey J.D. (2002) Cardiovascular solid mechanics: Cells, tissues, and organs. Springer Science+Business Media, New York.

Fung Y.C. (1997) Biomechanics: Circulation. Springer Science+Business Media, New York, second edition.

Holzapfel G.A., Ogden R.W. (2009) Biomechanical modelling at the molecular, cellular and tissue levels, CISM Courses and lectures, vol. 508. Springer, Wien.

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: