Cell biomechanics

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Synopsis:

The aim of the course is to explain basic structural and functional cell units and their importance for keeping mechanical integrity and ensuring motion. The subject is based on application of mechanical structure analysis to cellular structures.

Structure and morphology

Molecular forces, principles of self-organization

Mechanics of fluid mosaic

Helfrich energy

Mechanical cells with internal overpressure

Entropia of the ideal chain

Entropic elasticity

Elasticity of macromolecules

Elasticity of molecular networks

Tenzegrity principles

Experimental mechanics of molecules

Experimental cell mechanics

Molecular engines

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Study materials:

D. Boal (2012). Mechanics of the Cell, Cambridge University Press. ISBN: 9780521130691.

R.B. Phillips, J. Kondev, J. Theriot (2009). Physical Biology of the Cell, Garland Science. ISBN: 9780815344506.

K.A. Dill, S. Bromberg (2015) Molecular Driving Forces: Statistical Thermodynamics in Biology, Chemistry, Physics, and Nanoscience, 2nd Edition 2nd Edition, Garland Science; ISBN: 0815344309.

M. Gardel, Patrick Oakes (2015) Measuring Cell Mechanics. Biota Publishing. ISBN: 1615046992

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Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: