Biology

Vztahy:

In order to register for the course F7ABBBCH, the student must have successfully completed the course F7ABBBLG.

Garant předmětu:

Veronika Vymětalová

Lecturer:

Veronika Vymětalová

Tutor:

Veronika Vymětalová

Supervisor:

Department of Natural Sciences

Synopsis:

Basic information about the cellular level of organisms - from acelullar through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. Structure and conformation of biopolymers (nucleid acids and proteins). The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, vacuoles. Semiautonomic organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms.

Requirements:

Assessment: evolvement of laboratory practices, siccesful mastery of written work.

Examination: class ticket, succesful mastery of written work, oral exam

Syllabus of lectures:

Basic information about the cellular level of organisms - from acelullar through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, microbodies (glyoxisomes, peroxisomes), vacuoles. Semiautonomic organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Plant anatomy and histology. Types of plant cells and tissues. Tissue systems: meristems, epidermal, water-conducting and ground tissues, their structure and functions. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms. Gene therapy.

Syllabus of tutorials:

1. Microscopy. Microscopic Methods.

2. The preparation of the microscopic sample.

3. Prokaryotic cell microscopy.

4. Eukaryotic cell microscopy.

5. Cell Organelles microscopy.

6. Cell Organelles microscopy.

7. Cell division. Mitosis.

8. Cell plasmolysis.

9. Plant anatomy and organology.

10. Animal tissues.

11. Genetics - exercises.

12. Genetics - exercises.

13. Molecular biology.

Study Objective:

Basic information about the cellular level of organisms - from acelullar through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. Structure and conformation of biopolymers (nucleid acids and proteins). The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, microbodies (glyoxisomes, peroxisomes), vacuoles. Semiautonomic organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Plant anatomy and histology. Types of plant cells and tissues. Tissue systems: meristems, epidermal, water-conducting and ground tissues, their structure and functions. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms. Gene therapy.

Study materials:

[1] Alberts B., Bray D., Lewis J. a kol.: Molecular Biology of the Cell (4th ed.) Garland Science NY 2002, USA

Thomas D. Pollard and William C. Earnshaw: Cell Biology, Updated Edition, 2004, Elsevier

Note:

Time-table for winter semester 2024/2025:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
Tue
Wed
Thu	roomKL:B-223 Vymětalová V. 10:00–11:50 (lecture parallel1) Kladno FBMI Lab. mikroskopických praktikroomKL:B-223 Vymětalová V. 14:00–15:50 (lecture parallel1) Kladno FBMI Lab. mikroskopických praktik
Fri

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans:

• Prospectus - bakalářský (!)
• Biomedical Technology (compulsory course)