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CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2024/2025

Electroceuticals for Electrical and Magnetic Neurostimulation Therapies

The course is not on the list Without time-table
Code Completion Credits Range Language
F7ADIEC ZK 20P+8C English
Garant předmětu:
Lecturer:
Tutor:
Supervisor:
Department of Biomedical Technology
Synopsis:

Advances in bioelectromagnetics, electronics and neural engineering are setting the stage for a new era in medicine, where many diseases and conditions will be treated using electroceuticals: devices for electrical or magnetic neural stimulation. Considering that the human body and individual organs are fully controlled by the nervous system, a vast range of opportunities arise to tap into this system and generate therapeutic effects, without the common adverse side-effects of pharmaceuticals. This course will provide the prerequisite knowledge for understanding and for developing neurostimulation electroceuticals: basics of neural electrophysiology and bioelectromagnetics, a review of existing and emerging clinical applications, engineering challenges and solutions.

Requirements:

The subjects are concluded by an oral examination. The student must elaborate a paper on a given topic together with the exam in case of the controlled self-study. Assessment will be based on active participation in the discussion exercises, reports of group work and presentation of the research protocol conducted during the workshop.

The study is performed in the form of controlled self-study with regular consultations and obligatory participation in laboratory exercises.

Syllabus of lectures:

Lectures:

1.Nerve cells and resting membrane potential. Nerve excitation and action potential

2.Nerve modeling, stimulation waveforms and response thresholds

3.Basics of human neurophysiology, brain, spinal cord, peripheral nerves

4.Clinically used applications of neurostimulation

5.Emerging applications of neurostimulation

6.Clinically used therapeutic medical devices for electrical and magnetic neurostimulation

7.Novel therapeutic medical devices for electrical and magnetic neurostimulation

8.Bioelectronic interfaces, electrodes and applicators. Engineering challenges, constraints and solutions

9.Implanted bioelectronic devices: applications, miniaturization, energy efficiency and biocompatibility. Wireless power supply for bioelectronic implants

10.Electrical safety and electromagnetic compatibility aspects of electroceuticals, EMF exposure issues. Research, development and innovation of electroceuticals

Syllabus of tutorials:

Laboratory:

1.Therapeutic medical devices for electrical and magnetic neurostimulation

2.Dynamic modeling of EM-induced neuronal activation inhibition & synchronization

Study Objective:

Advances in bioelectromagnetics, electronics and neural engineering are setting the stage for a new era in medicine, where many diseases and conditions will be treated using electroceuticals: devices for electrical or magnetic neural stimulation. Considering that the human body and individual organs are fully controlled by the nervous system, a vast range of opportunities arise to tap into this system and generate therapeutic effects, without the common adverse side-effects of pharmaceuticals. This course will provide the prerequisite knowledge for understanding and for developing neurostimulation electroceuticals: basics of neural electrophysiology and bioelectromagnetics, a review of existing and emerging clinical applications, engineering challenges and solutions.

Study materials:

Required:

[1]J. P. Reilly and A. M. Diamant, Electrostimulation: Theory, Applications, and Computational Model, Boston, London: Artech House, 2011.

Recommended:

[1]Jaakko Malmivuo & Robert Plonsey: Bioelectromagnetism - Principles and Applications of Bioelectric and Biomagnetic Fields, Oxford University Press, New York, 1995.

[2]Biodesign: The process of innovating medical technologies, editors, Paul G. Yock, Stefanos Zenios, Joshua Makower, Todd J. Brinton, Uday N. Kumar, F. T. Jay Watkins; principal writer, Lyn Denend; Cambridge University Press, 2015.

Note:
Further information:
No time-table has been prepared for this course
The course is a part of the following study plans:
Data valid to 2024-03-28
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