Biosensors

Garant předmětu:

Bohuslav Rezek

Lecturer:

Bohuslav Rezek

Tutor:

Bohuslav Rezek

Supervisor:

Department of Physics

Synopsis:

This course introduces the physical, electronic, biological principles of biosensors and provides information on past, present and future technologies. Various mechanisms and sensor concepts for specific applications (such as detection of glucose, urea, proteins, cells, bacteria, etc.) are explained. In addition, the course introduces the use of modern nanostructures and nanomaterials in biosensors to achieve reliable and sensitive devices for diagnosis at the point of care, in food safety or environmental monitoring. We will also discuss current challenges and future perspectives for various applications of biosensors.

Requirements:

Students pass the exam by written test and oral examination. Students prepare reports from laboratory exercises.

Syllabus of lectures:

1.Overview of biosensors - Introduction and concept of biosensor

2.Biosensor development - ideal biosensor characteristics

3.Bioreceptor - catalytic (equilibrium) and affinity (equilibrium)

4.Surface Function - Physical and Chemical Immobilization

5.Electrochemical and Electrochemiluminescence - Overview and Applications

6.Optical - fluorescence and colorimetric study

7.Field controlled transistors - Sensors and applications

8.Nanobiosectors - top down (nanostructures)

9.Nanobiosectors - bottom up (nanomaterials)

10.BioMEMS / NEMS - Microfluidic, SAW

11.Application of biosensors - market for health care

12.Reliability of biosensors - in food and environment

13.New trends in biosensors - wearable biosensors, laboratory on chip

14.Current global biosensors challenges and future developments, final summary

Syllabus of tutorials:

The laboratory exercises introduce the construction and functional principles of biosensors in a practical and entertaining way. Exercises take place in the form of independent work of students in the laboratory and demonstrations.The exercises also include an excursion to collaborating research institutes.

Study Objective:

Study materials:

[1] New Perspectives in Biosensors Technology and Applications, Intech 2011, ISBN 978-953-307-448-1, doi:10.5772/936

[2] Biosensors, InTech 2010, ISBN 978-953-7619-99-2, doi:10.5772/45616

[3] Biosensors: fundamentals and applications, Oxford University Press 1989, ISBN 0198547455

Note:

Time-table for winter semester 2024/2025:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
Tue	roomT2:B2-48 Rezek B. 15:15–17:00 (lecture parallel1) Dejvice KonzultačníroomT2:B2-39e Rezek B. 17:00–18:45 (lecture parallel1) Dejvice Cvičebna
Wed
Thu
Fri

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans:

• Medical Electronics and Bioinformatics - Specialization Image Processing (compulsory elective course)
• Medical Electronics and Bioinformatics - Specialization Signal Processing (compulsory elective course)
• Medical Electronics and Bioinformatics - Specialization Bioinformatics (compulsory elective course)
• Medical Electronics and Bioinformatics - Specialization Medical Instrumentation (compulsory elective course)