Macromolecular Crystallography Laboratory 2

The course is not on the list Without time-table

Code	Completion	Credits	Range	Language
11PMK2	KZ	4	0+4	Czech

Garant předmětu:

Lecturer:

Tutor:

Supervisor:

Department of Solid State Engineering

Synopsis:

The subject introduces the students to computational approaches of macromolecular crystallography.

Requirements:

11DMSB - Diffraction Methods of Structural Biology

11PMK1 - Macromolecular Crystallography Laboratory 1

Syllabus of lectures:

Practicals only.

Syllabus of tutorials:

1. Phase problem solution - experimental phasing, molecular replacement.

2. Model building and structure refinement.

3. Structure validation procedures.

4. Databases.

Study Objective:

The goal of the study is practical experience with computational approaches in macromolecular crystallography: phase problem solution methods, structure refinement, structure validation. Final sessions are focused on work with structural and macromolecular databases.

Study materials:

J. Marek, Z. Trávníček: Monokrystalová rentgenová strukturní analýza. Univerzita Palackého v Olomouci, Olomouc, 2002.

V. Valvoda, M. Polcarová, P. Lukáč. Základy strukturní analýzy. Karolinum, Praha, 1992.

I. Kraus: Struktura a vlastnosti krystalů. Academia, Praha, 1993.

Note:

Further information:

https://kiplwww.fjfi.cvut.cz/drupal7/?q=11PMK2

No time-table has been prepared for this course

The course is a part of the following study plans:

Inženýrství pevných látek (elective course)