Thin Films in Medicine

Garant předmětu:

Lecturer:

Tutor:

Supervisor:

Department of Natural Sciences

Synopsis:

Overview of CVD and PVD thin film technologies. Lasers for material research

and thin films, mechanismus of film growth, analysis of properties of surfaces.

Application of thin films in medicine. Examples of coating of tooth prosthesis,

coating of heart valves, laser fabrication of biocompatible layers and organic

thin films for medicine and sensors.

Requirements:

Assessment: active participation on the solution of excercises

Examination: fulfillment of requirements for assessment, knowledges covering the

extent of the course

Syllabus of lectures:

Differences between PVD and CVD deposition technology, criteria for selection

of deposition technologies

Representatives of PVD and CVD technologies, principles, advantages,

disadvantages (growth rate, particles energy, pressure, limitations, depostited

area,..)

Evaporation and sputtering (diode sputtering, magnetron DC and RF) deposition

methods as IBAD, ion plating

Deposition methods - MBE, ECR, LPE, sol- gel, CVD

Laser and laser applications in material research. Pulsed laser deposition -

principle, advantages, disadvantages

Focusation of laser radiation (Gaussian beam, excimer laser, divergence, minimal

spot size, focusing length, quality of laser beam)

Interaction of laser radiation with matter - models, femtosecond ablation

Transport of material from target - plasma plume. Analyses of plasma plume (CCD

camera, influence of pressure and spot size, energy density, etc.)

Characterization of layer properties

. XRD (Bragg Brentanno, rocking curve,), FTIR, Raman, NMR,

Morphology - SEM, TEM AFM, STM, SNOM.

Analyses of layers composition and bonds - XPS, ESCA, AES, WDX, PIXE, RBS, SIMS,

WDX.

Optical methods for film characterization - ellipsometry, transmission, optical

reflection, refraction index, luminescence)

Mechanism of film growth - Frank- van der Merve, Volemr Veber, Stranski-

Krastanov) , homoepitaxy, heteroepitaxy

Medical applications of thon films (HA layers, DLC layers, coating of prothesis,

heart valves,, biocompatibbe materials.

Syllabus of tutorials:

Excercises follow the content of the lecture.

Study Objective:

To present basic principles of technology for thin film preparation with focus on laser deposition. Applications of thin layers in medicine.

Study materials:

[1] Chrisey D.B., Hubler G.K.: Pulsed Laser Deposition of Thin Films, Wiley and

Sons Inc., 1994,

[2] Mattox D.M.: Handbook of PVD Processing, Noyes Publications, 1998

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: