Logo ČVUT
CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2024/2025

Introduction to Bioinformatics

The course is not on the list Without time-table
Code Completion Credits Range Language
01UBIO KZ 2 2 Czech
Garant předmětu:
Lecturer:
Tutor:
Supervisor:
Department of Mathematics
Synopsis:

Bionformatics belongs to one of fastest progressing area of the human research. In more general understanding, any nontrivial application of methods from the computer science to biology can be seen as bioinformatics. This course is aimed mainly to analysis of DNA sequences and proteins. However, the algorithms being taught in this course find applications in many other areas.

Requirements:

Basics of algorithms on the level of the course Basics of algoritmization.

Syllabus of lectures:

1. Introduction to molecular biology

2. DNA mapping

3. Motif finding

4. Genome rearrangement (reversal sort)

5-7. Sequence alignment (dynamic programing)

8. Gene prediction

9. DNA sequencing

10. Protein identification

11. Combinatorial pattern matching (suffix trees)

12. Clustering, Hidden Markov Models

Syllabus of tutorials:

1. Reversal sort

2. Dynamic programming

3. Suffix trees

4. Clustering

Study Objective:

Knowledge:

DNA mapping, DNA sequencing, comparing sequences, genes prediction, proteins identification, motif finding, phylogenetic trees reconstruction, dynamic programming, clustering, suffix trees.

Skills:

Student will be able to apply the algorithms being teached to some simple problems in DNA sequence or protein analysis. These algorithms can be also used for advanced text and data set processing.

Study materials:

Key references:

N. C. Jones, P. A. Pevzner, An introduction to bioinformatics, MIT Press, 2004.

Recommended references:

W.-K. Sung, Algorithms in bioinformatics - a practical introduction, CRC Press, 2010.

Media and tools:

Note:
Further information:
No time-table has been prepared for this course
The course is a part of the following study plans:
Data valid to 2024-05-28
Aktualizace výše uvedených informací naleznete na adrese https://bilakniha.cvut.cz/en/predmet1594706.html