Bio system man

Garant předmětu:

Lecturer:

Tutor:

Supervisor:

Department of Biomedical Technology

Synopsis:

INTRODUCTION4 hours

System biology, physiology and medicine

Thermodynamics of living systems, origins of life: hazard or necessity?

Recall of physical laws applied to biology

FROM CELL TO TISSUES AND ORGANS

Cell structure and basic functions

Cell energetics: genesis and use of chemical, mechanical, electrical and thermal energy

Functional hierarchy of living organisms, from genotype to phenotype, principles of homeostasis and adaptation

Requirements:

Syllabus of lectures:

6.5. 2016: Cell, membrane thermodynamics, membrane proteins, transport kinetics & energetics.

13. 5. 2016: Convection: fluids, gases.

20. 5. 2016: Transcellular transports. Transports in artificial organs.

27.5. 2016: Information, neural signalling, origin and use of mechanical force.

Syllabus of tutorials:

Study Objective:

At the end of this cycle the student should

- understand the functional organisation of living organisms

- understand the basic concepts needed for a systemic approach to the human organism

- possess a good insight into integrated human functions interesting for bio-engineers

- be acquainted with experimental and investigation methods of the human physiology and medicine

- define interesting problems and propose their solving

- possess a sufficient vocabulary for an effective communication between engineers and physicians

Study materials:

Denis Noble: The MUSIC of LIFE Oxford University press, 2008

Hiroaki Kitano et al. : Systems Biology: A Brief Overview Science 295, 1662 (2002);

Hiroaki Kitano: Computational systems biology Nature 420, 206 (2002)

Marie E. Csete, & al. : Reverse Engineering of Biological Complexity Science 295, 1664 (2002)

Note:

Further information:

Course may be repeated

No time-table has been prepared for this course

The course is a part of the following study plans: