Electrophysiology

Grading of the course requires grading of the following courses:

Anatomy and Physiology II (17KBBAF2)

Lecturer:

Tutor:

Supervisor:

Department of medical branches and humanities

Synopsis:

The study subject links to Anatomy and Physiology II and is dedicated to excitable tissues (muscles and neural system) in the terms of signal generation, measurig possibilities and exploitation of changes in electrical parameters. Signal generation is explained at cellular molecular levels, different software simulations are employed. From the methodological point of view, measurements of electrical parameters are described at all levels - cells, tissues, organs. Exploitation of electrical parameters of cells, tissues and organs is treated from both clinical and experimental points. Methods to use electrical field or stimulation for medical purposes are described. Besides lectures, practical classes focused on independent study of students are incorporated into syllabus.

Requirements:

credit:

attendace at classes and protocols from classes.

exam: written test, multiplechoice, number of questions 36 classification according to directions.

Syllabus of lectures:

1. - 3. General electrophysiology- introduction, history,

membrane of excitable tissues, action and resting

membrane potential, nerve and synapse

4. - 7. Heart and ECG - history, signal generation, typical ECG curve, clinical use

8. - 11.Brain and EEG - history, signal generation, brain

wave rhythms, clinical use, sleep/wake cycle

12.-13. Other use of electrophysiology in research and

clinical practise - pain and epilepsy diagnosis and treatment, patch-clamp, voltage-clamp, single unit recording, evoked potentials

Syllabus of tutorials:

1st - 4th ECG - ECG recording and evaluation

5th - 9th EEG - EEG recording and evaluation

10th - 13th Cardiostimulators and basics in clinical patophysiology of heart - pathological ECG, disorders of heart conductive system, indication of cardiostimulation and defibrilation

Study Objective:

To inroduce a theory of origin of electrical phenomena in cells, possibilities of measurement and utilization of these phenomena in gifferent structural levels. Influence of electrical stimulation and practical exhibition of measurement of ECG and EEG.

Study materials:

Berne, Levy, Medical physiology, knihovna FBMI

Berne, Levy, Case studies for medical physiology, knihovna FBMI

Silbernagl S., Lang A.: Color atlas of patophysiology, Thieme, 2003

www stránka: physiome.org

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans:

• Bakalářský studijní obor Biomedicínský technik - kombinovaný (compulsory course)