Radiobiology and Radiation Protection
| Code | Completion | Credits | Range | Language |
|---|---|---|---|---|
| 17BPRRO | Z,ZK | 4 | 2+1 | Czech |
- Lecturer:
- Jozef Sabol (gar.), Marián Liberko, Leoš Navrátil
- Tutor:
- Jozef Sabol (gar.), Marián Liberko, Leoš Navrátil
- Supervisor:
- Department of medical branches and humanities
- Synopsis:
-
The aim of this course is to acquaint students with the detailed mechanisms of action ionizing radiation on living organisms at all levels (subcellular, cellular, tissue and whole body) with respect to the source of radiation doses, frequency and extent of exposure, degree of development of the irradiated organism and its genotype including the possibility of reparation. Assessment of the impact if radiomodificators and simultaneous action of other physical and chemical raw material. Another topic will be the effects of radiation on the embryo and fetus, hereditary effects and late effects (especially carcinogenesis), along with basic theories of radiation protection.
- Requirements:
-
Active participation in seminars, including home preparation, required 100% attendance at seminars, absence can be excused only for serious and documented reasons for agreement with the exercises. The method of compensation shall exercise teacher. Credit will be awarded for essay submission of radiobiology issues that will be acceptable with the Head of exercise and a further test of the content of a given exercise and self-study. In the test, the student may use literature, Internet, mobile phone or consult with other students.
The written test is part of the combined credit of:
- ABC-type answers (possibly more correct answers) - correctly answered question 1 point
- The answer when it is necessary to respond in writing (very important issues) - 5 points
Students can reach the maximum number of 80 points, with the successful execution of final test is necessary to reach 60 points (75%) and more.
The test will take place again in the form of the test. The oral part is only in the case of an ambiguous assessment test or if the student wants to get better ranking trademark.
The written test is part of the examination again combined from:
- ABC-type answers (possibly more correct answers) - correctly answered question 1 point
- The answer when it is necessary to respond in writing (very important issues) - 5 points
Students can reach the maximum number of 80 points, with the successful passing of the examination is necessary to reach 60 points (75%) and more.
Rating ECTS:
A good 100-90 (excellent)
B 89-80 very good (very good)
C 79-70 well (good)
D 69-60 satisfactory (satisfactory)
E 59-50 enough (sufficient)
F 49-0 failed (failed)
- Syllabus of lectures:
-
Radiobiology and the definition of units, physical and chemical processes occurring in the absorption of radiation damage to DNA.
DNA repair processes.
Chromosomal aberration biodozimeter.
Survival of cells, restoring their function, the dose rate effect.
Effects of radiation on cell cycle.
Effects of radiation on the level of tissues and whole body.
Clinical radiobiology.
Effects of radiation on the embryo and fetus, hereditary effects, late effects of ionizing and non-ionizing radiation.
Radio modulatory, interaction of radiation with chemicals.
Basics of Radiation Protection.
Basics of Radiation Protection.
- Syllabus of tutorials:
-
Sources of ionizing radiation.
Sources of non-ionizing radiation.
Molecular techniques in radiobiology.
Cytometric techniques in radiobiology.
Forecasting procedures in clinical radiobiology. Comparison of late effects of radiation and chemical nox.
Basics of radiation protection.
- Study Objective:
-
The course is in the field of ionizing radiation. Radiobiology clarifies the nature of different types of external radiation damage and contamination by radioactive substances, while offering biological explanations for the effects depending on the type and dose of radiation, the distribution of benefits over time, dose distribution in the body and the importance of repair processes. Attention will be devoted to various pathogenic forms of acute radiation sickness, the periodization of the clinical picture, further diagnosis, prophylaxis and the treatment of this disease. Students will become familiar with the risk of chronic radiation sickness, with late and genetic effects of radiation; they will be briefed in growth disorders and teratogen effects of ionizing radiation. Moreover, students will acquire basic knowledge in radiation protection, and will be able to analyze and evaluate the risk of exposure to specific ways of using sources of ionizing radiation in a given company.
- Study materials:
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[1] Navrátil, L., Kuna, P. a kol.: Klinická radiobiologie. MANUS, Praha, 2005
[2] Kuna, P. a kol.: Vojenská radiobiologie. VLA JEP, Hradec Králové, 1991
[3] Navrátil, L., Rosina, J. a kol.: Lékařská biofyzika. Grada, Praha, 2005
[4] Steel, G.G.: Basic Clinical Radiobiology. Edward Arnold, London, 1993
[5] Hall, E.J.: Radiobiology for the Radiologist. Lippincott, Philadelphia, 2000
- Note:
- Time-table for winter semester 2011/2012:
-
06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon Tue Fri Thu Fri - Time-table for summer semester 2011/2012:
- Time-table is not available yet
- The course is a part of the following study plans: