Basics of Biology

Lecturer:

Ivan Dylevský (gar.), Marián Liberko (gar.)

Tutor:

Marián Liberko (gar.)

Supervisor:

Department of medical branches and humanities

Synopsis:

Students will be introduced to the basics of a general biology course. They will discuss in particular the chapters on cellular and subcellular levels. Chapters will be routed to and related to general biology, the organization of living systems, organization and functioning of cells. Cytology (cell as a system of biological membranes and their functions, membrane organelles, Cytoskeletal structures), molecular and cellular biology, biopolymers (nucleic acids and proteins), molecular genetics (genetic information, replication, transcription and translation), mutations, cell cycle (mitosis, meiosis, their regulation), differentiation and aging, cell death (apoptosis and necrosis), cellular factors and external environmental factors, the basics of genetics - phenotype and genotype, hybridization methods, Mendel's laws, basic cytogenetics. Fundamentals of Human Genetics, and gonosomal autosomal inheritance, the human karyotype, chromosomal aberrations. Modern methods of studying the human genome, the genetic control of metabolism, pharmacogenetics, Immunogenetics, genetics and medicine, population biology, evolution of living systems.

Requirements:

During the semester, prepare, commit and defend each student seminar paper on which the student chooses at the beginning of the semester according to the offer.

Demonstrating knowledge test with a success rate above 80%.

Syllabus of lectures:

Introduction to the organization of living systems, the hierarchy of living systems

Cytology - the construction of prokaryotic and eukaryotic cells

Cell Biochemistry

Molecular biology (nucleic acids, the central dogma of molecular biology

Proteins - structure and function

Defense seminar papers

Cell cycle. Mitosis and meiosis. Their regulation. Differentiation and aging. Cell death.

Genetics I

Genetics II

Defense seminar papers

Syllabus of tutorials:

N/A

Study Objective:

Students will be introduced to the basics of general biology. They will discuss in particular the chapters on cellular and subcellular levels. Chapters will be routed to and related to general biology, the organization of living systems, organization and functioning of cells.

Study materials:

Literatura referenční

O. Nečas a kol. - Obecná biologie pro lékařské fakulty. H+H Jinočany 2000

S. Rosypal a kol. - Nový přehled biologie. Scientia Praha 2003

Literatura doporučená

B. Alberts et al. - Základy buněčné biologie. Espero Publishing 1998

J. Kapras, M. Kohoutová - Kapitoly z lékařské biologie a genetiky I. Karolinum

M. Soukupová, F. Soukup - Kapitoly z lékařské biologie a genetiky II. Karolinum

J. Kapras, M. Kohoutová - Kapitoly z lékařské biologie a genetiky III. Karolinum

Note:

Time-table for winter semester 2011/2012:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon	roomKL:B-709 Liberko M. 10:00–11:50 (lecture parallel1) Kladno FBMI Lab. anatomie a fyziologie
Tue
Fri
Thu
Fri

Time-table for summer semester 2011/2012:

Time-table is not available yet

The course is a part of the following study plans:

• Bakalářský studijní obor Plánování a řízení krizových situací - prezenční (compulsory course)