Fundamentals of medical Chemistry and Biochemistry

Lecturer:

Jaroslav Racek (gar.), Zdeněk Hon

Tutor:

Radka Dušková, Zdeněk Hon

Supervisor:

Department of medical branches and humanities

Synopsis:

Structure and function of cellular compartments. Structure and function of proteins. Enzymes as catalysts. Bioenergetics. Biological oxidation. Biogenic amines. Biochemistry of hormones and cytokines, hormonal regulation. Biologically important radicals. Metabolism of saccharides, lipids and lipoproteins, amino acids, proteins, nucleotides and nucleic acids. Regulation of the metabolism at cellular and organ levels. Biochemistry of the digestive tract, pancreas, biochemistry of the liver and metabolism of xenobiotics. Biochemistry of the kidneys. Biochemistry of tetrapyrroles and porphyrins. Biochemistry of muscles and bones. Biochemistry of the nervous system. Biochemistry of the blood, haemocoagulation and fibrinolysis. Metabolism of body fluids and ions, acidobasic equilibrium.

Requirements:

For the credit requires 86% attendance at seminars (perhaps one absence). Another condition is the processing of paper on a given topic, including its presentation at seminars (presentation of 20 to 25 min. On a given topic, presentations prepared in PowerPoint).

It is a written form, a test with the chosen answers. The test is open to only students who have been granted credit. Retake the test is also writing with at least one week apart. The test is open to only students who have been granted credit. The test contains a total of 30 test questions: Score: 30 to 29 correct answers = 1 (A) 28 to 27 correct answers = 1.5 (B) 26 to 24 correct answers = 2 (C) 23 to 22 correct answers

Syllabus of lectures:

Lectures:

Importance in biochemistry in medical branches.

Biochemistry of body fluids. Organic compounds.

Saccharides - structure, characteristics and importance.

Lipids - structure, characteristics, classification and importance.

Amino acids, peptides and proteins - importance and classification.

Syllabus of tutorials:

Practical exercises:

1st - 2nd weeks Principles of laboratory medicine. Instrumentation.

3rd - 4th weeks Organic compounds.

5th - 6th weeks Saccharides.

7th - 8th weeks Lipids.

9th - 10th weeks Amino acids, peptides and proteins.

Study Objective:

Targets:

to master basic knowledge within the subject to the extent necessary for the performance of the profession in the branch Radiology Assistant.

Study materials:

[1] Habermann, V.: Lékarská chemie. Praha: Karolinum, 2004, ISBN 80-246-0789-1.

[2] Bruce, A., et al.: Základy bunecné biologie: úvod do molekulární biologie bunky. Ustí nad Labem: Espero, 2006, ISBN 80-902906-2-0.

[3] Trojan, S., et al.: Lékarská fyziologie, Praga: Grada, 2003, ISBN 80-247-0512-5.

[4] Rezácová, M., Stoklasová, A.: Základy biochemie lidského organismu, Praha: Karolinum, 2008, ISBN 978-80-246-1510-3.

[5] Patocka, J.: Uvod do obecné toxikologie. Praha: Manus, 2003. ISBN 80-86571-04-1.

[6] Racek, J. a kol.: Klinická biochemie. 2. vydání, Praha: Galén, Karolinum, 2006. ISBN 80-7262-324-9

[7] Stern, P. a kol.: Obecná a klinická biochemie. Karolinum: Praha 2005. ISBN 80-246-1025-6

[8] Kodícek, M.: Biochemické pojmy - vykladovy slovník, verze 2.0 [online]. VSCHT v Praze: 2007. Dostupné online (http://vydavatelstvi.vscht.cz/knihy/uid_es-002/). ISBN 978-80-7080-669-2.

[9] Sofková, D., a kol.: Biochemie - základní kurz. Karolinum: Praha 2005. ISBN 80-7184-936-7

Note:

Time-table for winter semester 2011/2012:

Time-table is not available yet

Time-table for summer semester 2011/2012:

Time-table is not available yet

The course is a part of the following study plans:

• Bakalářský studijní obor Radiologický asistent - prezenční (compulsory course)