Modelling physiological systems

Lecturer:

Tutor:

Supervisor:

Department of Biomedical Informatics

Synopsis:

Completion of the modeling metodology from the subject Modeling and simulation, in particular the design of a new experiment, respectively additional experiment. Examples of physiological models from practice (BRS model, a model of renal function within stabilizing blood pressure, pulse model of blood circulation, model of the isometric contraction of skeletal muscle)

Requirements:

participation in exercises (max 10 points)

2 homeworks (max. 40 points)

Syllabus of lectures:

1.Repeating the methodology of modeling of biological systems

2.Metodology of the design of an additional experiment

3.Baroreflex model

4.Model of renal function within stabilizing blood pressure

5.Pulse model of blood circulation

6.Model of the isometric contraction of skeletal muscle

7.Model of glucose regulation, regulatory model of gastric acidity

Syllabus of tutorials:

1.Repeating the methodology of modeling of biological systems on the selected example

2.Examples of a design of new respectively additional experiment in program MWPharm

3.Baroreflex model

4.Model of renal function within stabilizing blood pressure

5.Pulse model of blood circulation

6.Model of the isometric contraction of skeletal muscle

7.Assessment

Homeworks:

1. Another example of a design of new respectively additional experiment in program MWPharm

2. Regulatory model of gastric acidity

Study Objective:

to provide students with a methodology of design and implementation of mathematical models of selected physiological systems

Study materials:

[1]van Wijk van Brievingh R.P., Moeller D.P.F. (ed.) Biomedical Modeling and Simulation on a PC (A Workbench for Physiology and Biomedical Engineering), New York Springer Verlag, 1993

[2]Keener J., Sjezd J.: Mathematical Physiology. New York Springer Verlag, 1998

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans:

• Navazující magisterský studijní obor Přístroje a metody pro biomedicínu - prezenční v angličtině (compulsory elective course)