Physical Phenomena Modeling in COMSOL MULTIPHYSICS

Course guarantor:

David Vrba

Lecturer:

David Vrba, Jan Vrba

Tutor:

Matouš Brunát, David Vrba

Supervisor:

Department of Biomedical Technology

Synopsis:

Numerical simulations are increasingly being used to develop new and optimize existing products and devices. Numerical simulations can greatly reduce the number of prototypes needed and thus significantly accelerate and reduce development costs. Another sector where numerical simulations are used is a sector where it is difficult to verify ongoing physical processes (eg, heating the biological tissue under electrodes for direct brain simulation). Last but not least, based on numerical simulations, we can plan treatment where, based on knowledge of material properties, we can define the amount of power delivered to the device (eg radiofrequency ablation in oncology or cardiac surgery). Computer modeling involves the creation of geometry, setting of material properties and boundary conditions and, last but not least, the choice of differential equations, the method of discretization of the computing area and the processing of results. The accuracy of the results obtained, the length of calculations and the computational power requirements are very dependent on the numerical model setting. The lectures cover the most common problems in electrical engineering, thermics, mechanics, chemistry, acoustics and fluid dynamics. The acquired knowledge will be tested by the students when designing individual parts of devices and devices.

Requirements:

The requirements for successful completion of the subject:

1. Creating and presenting a functional model in the COMSOL program on a topic chosen by the student from the list prepared by the lecturer

2. Submission of a two-page summary of one professional article dealing with the use of COMSOL Multiphysics in biomedicine

Syllabus of lectures:

1. Overview of the most frequently used numerical methods and finite element (FEM) and finite time domain (FDTD). Overview of SW for creating a real anatomical model.

2. Simulation of electrical and magnetic field for static and quasi-static applications (AC / DC Module), calculation of electric field distribution around the electrodes of pacemaker and electrosurgical device

3. Electromagnetic field simulation (RF Module), design and modeling of high-frequency devices

4. Equation of heat dissipation in biological tissues, in particular the Penetration Equation (Heat Transfer Module), Multiphysical simulations.

5. Finite Element Method

6. Acoustics Module, Thermoablation with High Intensity Focused Ultrasound

7. Fluid Mechanics - One Phase (CFD Module)

Syllabus of tutorials:

1. Introduction to Comsol Multiphysics, 3D geometry creation, grid and solver setting.

2. Calculating the electric field distribution around the pacemaker electrodes.

3. Modeling of the waveguide applicator for local hyperthermia and electromagnetic field generated in the biological tissue.

4. Extension of the previous model on temperature simulation in biological tissue.

5. Creation of a real anatomical model in the program Mimics and 3-Matic (Materialize).

6. Fluid Mechanics - one phase and more immiscible phases using the Level Set Method.

7. Light transmission in optical fiber. Creating a model in COMSOL Multiphysics, exporting and editing, executing simulations and analyzing results in MATLAB.

Study Objective:

The course aims to introduce the possibilities offered by current numerical simulation of physical phenomena, particularly in relation to biomedical engineering. For these purposes, the COMSOL Multiphysics software platform will be used to perform numerical simulations of individual physical phenomena and their combinations. Furthermore, students will try to create a real anatomical 3D model using segmentation in Materialise Mimics and 3-Matic. This model will be used for numerical simulation in COMSOL or will be printed on a 3D printer.

Study materials:

[1] COMSOL Multiphysics (COMSOL AB, Stockholm, Sweden)

[2] Reddy, J.N. (2006). An Introduction to the Finite Element Method (Third ed.). McGraw-Hill. ISBN 9780071267618.

Note:

Time-table for winter semester 2024/2025:

	06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
Tue	roomKL:B-730 Brunát M. Vrba D. 14:00–15:50 EVEN WEEK (lecture parallel1 parallel nr.1) Kladno FBMI roomKL:B-433 Vrba D. Vrba J. 14:00–15:50 ODD WEEK (lecture parallel1) Kladno FBMI
Wed
Thu
Fri

Time-table for summer semester 2024/2025:

Time-table is not available yet

The course is a part of the following study plans:

• Prospectus - bakalářský (!)
• Biomedical Technology (compulsory elective course)
• Biomedical Technology (compulsory elective course)