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CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2020/2021

Health risks of ionizing radiation

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Code Completion Credits Range
16ZRIZ ZK 2 2P+0C
Lecturer:
Marie Davídková (guarantor), Tomáš Vrba
Tutor:
Supervisor:
Department of Dosimetry and Application of Ionizing Radiation
Synopsis:

The aim of the course is to acquaint students with the radiobiological basics of radiation protection. The basis of the course is an introduction to the biological effects of ionizing radiation (IR) at the molecular, cellular and tissue levels, an overview of deterministic and stochastic effects of ionizing radiation, health harm, risk and its evaluation, basics of epidemiology.

Requirements:

Required prerequisities are 16ZDOZ1, 16URF2.

Syllabus of lectures:

1. Introduction.

2. Time course of effects of IR

3. Primary radiation damage at the molecular level

4. Radiation damage at the cellular level

5. Radiation damage to tissues and organs

6. Deterministic effects of IR

7. Stochastic effects of IR, genetic effects of IR

8. Experimental methods of measuring the effects of IR on humans

9. Measurement of low dose radiation effects, biodosimetry

10. General epidemiology

11. Types of epidemiological studies and their properties

12. Epidemiological studies investigating the influence of IR

13. Determination of injury and risk with respect to IR

Syllabus of tutorials:
Study Objective:

Knowledge:

radiolysis of water, mechanisms of biological effect of IR on subcellular, cellular and tissue levels, fundamentals of radio-epidemiology, influence of epidemiological studies on radiation protection

Abilities:

Orientation in problematic radiobiology and epidemiology for radiation protection.

Study materials:

Key references:

[1] UNSCEAR 2017 REPORT Sources, Effects And Risks Of Ionizing Radiation, 2017

[2] ICRP Publication 103 - Recommendations of the International Commission on Radiological Protection, 2007

Recommended references:

[3] Lehnert, S.: Biomolecular action of ionizing radiation, Taylor&Francis, 2008

[4] Nias A.H.W.: An introduction to radiobiology, Wiley, Chichester, 2000

[5] Joiner M., van der Kogel A.: Basic Clinical Radiobiology, Taylor&Francis, 2009

Note:
Time-table for winter semester 2020/2021:
Time-table is not available yet
Time-table for summer semester 2020/2021:
Time-table is not available yet
The course is a part of the following study plans:
Data valid to 2021-03-02
For updated information see http://bilakniha.cvut.cz/en/predmet5952406.html