Health risks of ionizing radiation

Garant předmětu:

Marie Davídková

Lecturer:

Marie Davídková

Tutor:

Supervisor:

Department of Dosimetry and Application of Ionizing Radiation

Synopsis:

The aim of the course is to acquaint students with the radiobiological basics of radiation protection. The basis of the course is an introduction to the biological effects of ionizing radiation (IR) at the molecular, cellular and tissue levels, an overview of deterministic and stochastic effects of ionizing radiation, health harm, risk and its evaluation, basics of epidemiology.

Requirements:

Required prerequisities are 16ZDOZ1, 16URF2.

Syllabus of lectures:

1. Introduction.

2. Time course of effects of IR

3. Primary radiation damage at the molecular level

4. Radiation damage at the cellular level

5. Radiation damage to tissues and organs

6. Deterministic effects of IR

7. Stochastic effects of IR, genetic effects of IR

8. Experimental methods of measuring the effects of IR on humans

9. Measurement of low dose radiation effects, biodosimetry

10. General epidemiology

11. Types of epidemiological studies and their properties

12. Epidemiological studies investigating the influence of IR

13. Determination of injury and risk with respect to IR

Syllabus of tutorials:

Study Objective:

Knowledge:

radiolysis of water, mechanisms of biological effect of IR on subcellular, cellular and tissue levels, fundamentals of radio-epidemiology, influence of epidemiological studies on radiation protection

Abilities:

Orientation in problematic radiobiology and epidemiology for radiation protection.

Study materials:

Key references:

[1] UNSCEAR 2017 REPORT Sources, Effects And Risks Of Ionizing Radiation, 2017

[2] ICRP Publication 103 - Recommendations of the International Commission on Radiological Protection, 2007

Recommended references:

[3] Lehnert, S.: Biomolecular action of ionizing radiation, Taylor&Francis, 2008

[4] Nias A.H.W.: An introduction to radiobiology, Wiley, Chichester, 2000

[5] Joiner M., van der Kogel A.: Basic Clinical Radiobiology, Taylor&Francis, 2009

Note:

Time-table for winter semester 2023/2024:

Time-table is not available yet

Time-table for summer semester 2023/2024:

Time-table is not available yet

The course is a part of the following study plans:

• Jaderné inženýrství - Aplikovaná fyzika ionizujícího záření (PS)
• Radiologická technika (compulsory course in the program)
• jaderné inženýrství - Radioaktivita v životním prostředí (PS)
• Vyřazování jaderných zařízení z provozu (compulsory course in the program)