Biochemistry

The course 17PBOBCH can be graded only after the course 17PBOCHM has been successfully completed.

Garant předmětu:

Lecturer:

Tutor:

Supervisor:

Department of Natural Sciences

Synopsis:

Cell compartments structure and functions. Protein structure and function. Enzymes as catalysts. Bioenergetics. Biological oxidation. Biogenic amines. Hormones biochemistry, hormonal regulation. Biologicaly significant radicals. Metabolism of sacharides, lipids and lipoproteins, amino-acids, proteins, nucleotides and nucleic acids. Regulation of metabolism on a cell and organ level. Biochemistry of the intestinal tract, pancreas, biochemistry of liver and xenobotics metabolism. Biochemistry of kidneys. Biochemistry of tetrapyrols and porfyrins. Biochemistry of muscles, bones. Biochemistry of nervous system. Biochemistry of blood, hemocoagulation process and fibrinolisys. Metabolism of body fluids and ions, acidobasic balance.

Requirements:

Credit condition: attendance min. 80%, succesfull passing of written tests, basic biochemical compounds formulae, chosen theme presentation on seminary

Exam condition: succesfull passing of written test, 30 questions, one correct answer, success in obtaining at least 60% accuracy, oral exam

Syllabus of lectures:

1.Clinical biochemistry, clinical laboratory.

2.Pathology of metabolisms of sacharides.

3.Clinical biochemistry of cardiovasculary system.

4.Clinical biochemistry of digestive tract, liver and nutrition.

5.Clinical biochemistry of reniculus, hormonal system.

6.Biochemistry of heredity, nucleic acids.

7.Biochemistry of vision.

Syllabus of tutorials:

1.Biochemistry, structure and function of cells compartments

2.Sacharids, structure, metabolism, failure of metabolism

3.Lipids, structure, metabolism, failure of metabolism.

4.Aminoacids, metabolism, failure of metabolism.

5. Proteins, structure and function, biological importance.

6.Enzyms, funce, function, biological importance.

7. Biochemistry visceral liquid, ions, acidobazic equilibrium.

Study Objective:

Mastering of theroretical biochemistry knowledge. Mastering of metabolism overview, and its relations with natural moleculs chemistry.

Study materials:

Required Literature:

1.VOET, Donald a Judith G. VOET. Biochemistry. 3. ed. Hoboken, NJ: Wiley, 2004.

2.BERG, Jeremy M., John L. TYMOCZKO a Lubert STRYER. Biochemistry. 6th ed. New York: W. H. Freeman, 2007.

3.CHAMPE, Pamela C., Richard A. HARVEY a Denise R. FERRIER. Lippincott's illustrated reviews: biochemistry. 4th ed. Philadelphia: Wolters Kluwer, 2008.

Note:

Further information:

https://harm.fbmi.cvut.cz/B231/F7PBOBCH/tut https://harm.fbmi.cvut.cz/B231/F7PBOBCH/lec

No time-table has been prepared for this course

The course is a part of the following study plans: