Biological Effects of Ionizing Radiation
- Department of Health Care Disciplines and Population Protection
The lectures will give an overview of basic radiation biology. Students will become familiar with the biological effects of ionizing radiation: the physical and chemical processes by which radiation causes damage to the biological material; mechanisms of radiation action on the DNA and other constituents of the cell; types of damage and their repair; subcellular and cellular sensitivity and radiation response; physical, chemical and biological modifiers of radiation action; theories and models of cellular survival; and radiation biology of normal and neoplastic tissues.
demonstration of the knowledge mastered by a written 2 tests, always 50 % success rate.
Oral examination on the basis of the decision field supervisor.
note: the interval between testing and the outcome in due time or the corrective terms must be at least seven days.
- Syllabus of lectures:
1st Week - Introduction
2nd week - Atomic structure. Radioactivity
3rd week - Types and properties of ionizing radiation. Sources of ionizing radiation. Interaction of ionizing radiation with matter
4th Week - Radiation protection. Radioprotection
5th Week - TEST 1
6th Week - Interaction of ionizing radiation with tissue
7th week - DNA damage repair, DNA damage and cell cycle
8th Week - Deterministic and stochastic effects
9th Week - Use of ionizing radiation in medicine
10th Week - Radiation accidents
11th Week - Excursion
12th week - Excursion
13th Week - Consultation
14th week - TEST 2
Note - The order of presentations may change, students will be informed.
- Syllabus of tutorials:
- Study Objective:
Ionizing radiation. Non-ionizing radiation. Interaction of ionizing radiation with tissue. Deterministic and stochastic effects. DNA damage repair, DNA damage and cell cycle. Basics of radiation protection.
- Study materials:
1. HALL, Eric J. a Amato J. GIACCIA. Radiobiology for the radiologist. 7th ed. Philadelphia: Wolters Kluwer :Lippincott Williams & Wilkins, 2012.
2. STEEL, G. Gordon., ed. Basic clinical radiobiology. 3rd ed. London: Arnold, 2002.
- Further information:
- No time-table has been prepared for this course
- The course is a part of the following study plans: