Organic Chemistry 2

Garant předmětu:

Lecturer:

Tutor:

Supervisor:

Department of Nuclear Chemistry

Synopsis:

Introduction to the main groups of organic compounds and important groups of compounds - industrial and natural.

Requirements:

Knowledge of chemistry on the level of a graduate from a secondary grammar school. Completed course Organic Chemistry 1.

Syllabus of lectures:

1.Natural sources of organic chemistry - coal, petroleum, natural gas, wood, plants, biotechnology. Components of crude petroleum and tar and their separation.

2.Industrial production of fuels from petroleum and coal. Production of methanol, ethanol, formaldehyde, acetic acid, benzoic acid, oxalic acid, phtalic anhydride and acid, phenol, ethene, propene, butadiene, aniline.

3.Basic laboratory preparations - differences from the industrial scale. Oxidation, reduction, nucleophilic and electrophilic substitutions, additions, photochemistry. Principles of main laboratory techniques: crystallisation, distillation, chromatography.

4.Structure elucidation of organic compounds. History of, degradation to compounds with known structure. Some special reactions. Spectral analysis - mass spectra, NMR spectra, IR spectra, UV spectra, X-ray analysis.

5.Terpenoids: mono-, to poly-. Biosynthesis, reactions, properties and occurrence in the nature. Steroids: Nomenclature, biosynthesis, main skeletons, typical natural steroids, biological activity, hormones.

6.Carbohydrates: mono- to poly-. Nomenclature, natural occurrence, stereochemistry, Fischer and Haworth formulas, annomers. Properties of polysaccharides.

7.Glycosides, saponins, naturally occurring phenolic compounds. Lignine.

8.Aminoacids, peptides, alkaloids. Proteins, folding and structure. Biological importance, enzymes. Nucleic acids.

9.Waxes, lipids, natural essential oils, phospholipides, biological membranes.

10.Heterocycles, properties, reactivity, tar and its composition.

11.Natural dyes and natural polymers. Synthetic polymers - preparation, main classes, reactions, properties. Polyethylene, polyamides, polycondensates, vulcanization.

12.Medicals, drugs, poissonous compounds. History, main classes, preparation, properties, biomimetics. Biological activity prediction.

13.Detergents, pesticides, dyes, paints, explosives.

14.Fuels, rocket fuels, oils and lubricants, perfumery. Glues (silicon, epoxide, cyanoacrylate) and other organic compounds of practical interest.

Syllabus of tutorials:

Study Objective:

The course of organic chemistry provides the students with the knowledge of the main groups of organic compounds and important groups of compounds - industrial and natural.

The students will acquire competence to apprehend the advanced specialised chemistry courses.

Study materials:

Key literature:

1. McMurry Organic chemistry

2. Lewis D. E. Organic chemistry, A modern perspective, WCB Publishers 1996

Note:

Further information:

No time-table has been prepared for this course

The course is a part of the following study plans: