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CZECH TECHNICAL UNIVERSITY IN PRAGUE
STUDY PLANS
2018/2019

Biocompatibility and Corrosion Processes

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Code Completion Credits Range Language
17PMBBPK Z,ZK 5 2+2 Czech
Lecturer:
Libor Holík (guarantor)
Tutor:
Libor Holík (guarantor)
Supervisor:
Department of Biomedical Technology
Synopsis:

Purpose of this course is to introduce implant materials used for extracorporeal aplications in biomedicine. The emphasis is put especially on the theoretical basis of human body interactions with implant materials and metal corrosion in the human body. Practical work in the laboratory empower students to develope practical skills and work with the corrosive material.

Requirements:

Credit requirements:

Active attendance at all tutorials. Students has to come in time and be well prepared. Absences are acceptable for serious reasons only, have to be apologized and recompensed. Passing entrance test at least for 60% for each tutorial; if not, the tutorial including the test will be recompensed on another date.

Working out assigned exercises and submiting laboratory reports in satisfying quality.

Examination conditions: Student has to pass a written test comprising the topics discussed during the lectures and tutorials, including assigned individual study. The exam is graded according to the ECTS scale, to pass the exam, the test must be evaluated at least at 50 %.

Syllabus of lectures:

1. Introduction to corrosion and biokompatibility

2. Metal materials: structure, corrosion

3. Metal materials: corrosion cinetics, corrosion protection

4. Metal materials: aplication io biomedicine

5. Polymeric materials

6. Ceramics materials

7. Carbon, composite materials

8. Biodegradation, surface conversion

9. Protein adsorption , adhesion of cells, cells interactions with the surface

10. Biocompatibility testing, medicines legislation

11. Bacterial adhesion and infection,

12. Sterilisation of materials

13. Methods for determination of the structure and composition of materials

14. Progress in biocompatible materials

Syllabus of tutorials:

1. Introduction to biomechanics and basic calculations

2. Working with databases

3. Working with databases

4. Preparation of samples for corrosion experiments

5. Corrosion cinetic

6. Faraday's experiment

7. Evans experiment

8. Inhibition of the corrosion

9. Point corrosion

10. Time dependent of the corrosion rate

11. Macrocell corrosion

12. Corrosion in sulfuric acid

13. Efect of chloride concentration on the corrosion

14. Corrosion under extreme conditions

Study Objective:

The goal of study is to understand the biocompatibility and corrosion processes in biomedicine.

Study materials:

[1]Helsen, J.A., Breme, H.J.: Metals as Biomaterials, J.Willey & sons, N.Y., 1998

[2]Handbook of Biomaterials Properties, eds. Black J., Hastings G., Chapman&Hall, London 1998.

[3]Callister WD: Materials Science and Engineering: An Introduction, 5th edition, John Wiley & Sons, 2000.

Note:
Time-table for winter semester 2018/2019:
06:00–08:0008:00–10:0010:00–12:0012:00–14:0014:00–16:0016:00–18:0018:00–20:0020:00–22:0022:00–24:00
Mon
Tue
roomKL:B-420_N
Holík L.
16:00–17:50
(lecture parallel1)
Kladno FBMI
Učebna
roomKL:A-15
Holík L.
18:00–19:50
(lecture parallel1)
Kladno FBMI
Laboratoř chemie
Fri
roomKL:A-15
Holík L.
16:00–17:50
(lecture parallel1)
Kladno FBMI
Laboratoř chemie
roomKL:A-15
Holík L.
18:00–19:50
(lecture parallel1)
Kladno FBMI
Laboratoř chemie
Thu
Fri
Time-table for summer semester 2018/2019:
Time-table is not available yet
The course is a part of the following study plans:
Data valid to 2019-04-23
For updated information see http://bilakniha.cvut.cz/en/predmet2208706.html