Biocompatibility and Corrosion Processes
- Libor Holík (guarantor)
- Libor Holík (guarantor)
- Department of Biomedical Technology
Purpose of this course is to introduce implant materials used for extracorporeal aplications in biomedicine. The emphasis is put especially on the theoretical basis of human body interactions with implant materials and metal corrosion in the human body. Practical work in the laboratory empower students to develope practical skills and work with the corrosive material.
Active attendance at all tutorials. Students has to come in time and be well prepared. Absences are acceptable for serious reasons only, have to be apologized and recompensed. Passing entrance test at least for 60% for each tutorial; if not, the tutorial including the test will be recompensed on another date.
Working out assigned exercises and submiting laboratory reports in satisfying quality.
Examination conditions: Student has to pass a written test comprising the topics discussed during the lectures and tutorials, including assigned individual study. The exam is graded according to the ECTS scale, to pass the exam, the test must be evaluated at least at 50 %.
- Syllabus of lectures:
1. Introduction to corrosion and biokompatibility
2. Metal materials: structure, corrosion
3. Metal materials: corrosion cinetics, corrosion protection
4. Metal materials: aplication io biomedicine
5. Polymeric materials
6. Ceramics materials
7. Carbon, composite materials
8. Biodegradation, surface conversion
9. Protein adsorption , adhesion of cells, cells interactions with the surface
10. Biocompatibility testing, medicines legislation
11. Bacterial adhesion and infection,
12. Sterilisation of materials
13. Methods for determination of the structure and composition of materials
14. Progress in biocompatible materials
- Syllabus of tutorials:
1. Introduction to biomechanics and basic calculations
2. Working with databases
3. Working with databases
4. Preparation of samples for corrosion experiments
5. Corrosion cinetic
6. Faraday's experiment
7. Evans experiment
8. Inhibition of the corrosion
9. Point corrosion
10. Time dependent of the corrosion rate
11. Macrocell corrosion
12. Corrosion in sulfuric acid
13. Efect of chloride concentration on the corrosion
14. Corrosion under extreme conditions
- Study Objective:
The goal of study is to understand the biocompatibility and corrosion processes in biomedicine.
- Study materials:
Helsen, J.A., Breme, H.J.: Metals as Biomaterials, J.Willey & sons, N.Y., 1998
Handbook of Biomaterials Properties, eds. Black J., Hastings G., Chapman&Hall, London 1998.
Callister WD: Materials Science and Engineering: An Introduction, 5th edition, John Wiley & Sons, 2000.
- Time-table for winter semester 2018/2019:
- Time-table for summer semester 2018/2019:
- Time-table is not available yet
- The course is a part of the following study plans:
- Biomedical Engineering - full-time study (compulsory course)