Clinical Dosimetry

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Code Completion Credits Range
16KLD ZK 2 2+0
Tereza Hanušová (guarantor), Josef Novotný (guarantor)
Department of Dosimetry and Application of Ionizing Radiation

Specific requirements for radiation beam dosimetry as well as radiation protection aspects will be discussed for clinically used beams. Absolute and relative dosimetry methods including instrumentation and in-vivo dosimetry technology and their possibilities and limitations in clinical dosimetry will be analysed. Optimisation and minimization of absorbed dose from X-ray examinations, dose determination based on activity of applied radiopharmaceutical.


Required prerequisities are 16ZDOZ1, 16ZDOZ2, 16DETE.

Syllabus of lectures:

1. Clinical dosimetry subject, relation to other radiation sciences, requirements and uncertainties, quality assurance, role of medical physicists.

2. Standardisation in clinical dosimetry, concept of absorbed dose to water measurements for photon and electron beams.

3. Absorbed dose estimation in photon and electron clinical beams, determination of beam energy.

4. Dosimetric instrumentation for relative dose measurements in a water phantom. Measurement and evaluation, data transfer to a planning computer.

5. Measurements of kV X-ray radiation: energy specification, HVL measurements, filtration of the beam, parameters of beams, absorbed dose estimation, relative dose distributions.

6. Simulators and CT: target volume definition for treatment planning procedures, function of simulators, specification of simulator's parameters, role of CT scanners, CT functions, imaging on CT.

7. Brachytherapy: sealed radioactive sources, dosimetry of sealed and closed sources, manual and afterloading, practical aspects of dose evaluation.

8. Radiobiological models in radiotherapy: dependence dose-number of fraction and total dose, linear quadratic model, clinical application.

9. Quality assurance programme: basic concept, standards and recommendations for radiation therapy, QA manual, basic components of QA.

10. QA programme for radiation therapy units: radionuclide machines, linear accelerators, therapeutic X-ray units, brachytherapy instruments. Choosing and installing devices, acceptance and commissioning tests, stability and log term stability checks.

11. QA programme for simulators and CT units.

12. Radiation protection in radiotherapy: legislation, shielding calculations, acceptance of treatment rooms, monitoring of staff and patients, emergency planning, incidence and accident in radiotherapy.

Syllabus of tutorials:
Study Objective:


Knowledge of specific requirements for radiation beam dosimetry as well as radiation protection aspects for clinically used beams, dosimetry methods and their practical applications.


Optimizing and reducing doses of X-ray examinations and applications of radiopharmaceuticals.

Study materials:

Key references:

[1] F.M. Khan, The Physics of Radiation Therapy, 2nd ed. Williams and Wilkins, Baltimore, MD. 1994

[2] J.R.Williams, D.I. Thwaites, Radiotherapy Physics in Practice.2nd. ed. Oxford Univesity Press, N.Y. 1994

Recommended references:

[3] IAEA Techical Report Series No277: Absorbed Dose Determination in Photon and Electron Beams. An International Code of Practice. 2nd. ed. IAEA Vienna 1997

[4] IAEA Technical Report Series No381: The Use of Plane Parallel Ionization Chambers in High Energy Electron and Photon Beams. An Itarnational Code of Practice for Dosimetry. IAEA 1997

[5] IAEA Technical Report Series No398: Absorbed Dose Determination in External Beam Radiotherapy. An International Code of Practice for Dosimetry Based on Standards of Absorbed Dose to Water., IAEA Vienna 2000.

[6] ČSN ISO 9002: Quality Systems. Model for quality assurance in production and commissioning.(in Czech)

[7] AAPM (AMERICAN ASSOCIATION OF PHYSICISTS IN MEDICINE): Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group No. 40. Med.Phys. 21 (April 1994), 581 - 618.

Time-table for winter semester 2020/2021:
Time-table is not available yet
Time-table for summer semester 2020/2021:
Time-table is not available yet
The course is a part of the following study plans:
Data valid to 2021-03-05
For updated information see http://bilakniha.cvut.cz/en/predmet11371905.html